A programmed –1 ribosomal frameshift signal can function as a cis-acting mRNA destabilizing element

Nonsense-mediated mRNA decay (NMD) directs rapid degradation of premature termination codon (PTC)-containing mRNAs, e.g. those containing frameshift mutations. Many viral mRNAs encode polycistronic messages where programmed –1 ribosomal frameshift (–1 PRF) signals direct ribosomes to synthesize poly...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Plant, Ewan P., Wang, Pinger, Jacobs, Jonathan L., Dinman, Jonathan D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2004
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC373365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14762205/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh256
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!