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Encapsulating Immunostimulatory CpG Oligonucleotides in Listeriolysin O-Liposomes Promotes a Th1-Type Response and CTL Activity

Immunostimulatory sequences (ISS) are short DNA sequences containing unmethylated CpG dimers that have multiple effects on the host immune system, including the ability to stimulate antigen-specific cytotoxic T lymphocytes (CTLs) and drive Th1-type immune responses. Listeriolysin O (LLO)-containing...

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Detalhes bibliográficos
Main Authors: Andrews, Chasity D., Huh, Myung-Sook, Patton, Kathryn, Higgins, Debbie, Van Nest, Gary, Ott, Gary, Lee, Kyung-Dall
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3733356/
https://ncbi.nlm.nih.gov/pubmed/22376145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp2003835
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