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A real-time PCR assay for DNA-methylation using methylation-specific blockers

DNA methylation-based biomarkers have been discovered that could potentially be used for the diagnosis of cancer by detection of circulating, tumor-derived DNA in bodily fluids. Any methylation detection assay that would be applied to these samples must be capable of detecting small amounts of tumor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cottrell, Susan E., Distler, Jürgen, Goodman, Nancy S., Mooney, Suzanne H., Kluth, Antje, Olek, Alexander, Schwope, Ina, Tetzner, Reimo, Ziebarth, Heike, Berlin, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC373310/
https://ncbi.nlm.nih.gov/pubmed/14722226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gnh008
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