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Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2

Serine/threonine/tyrosine-interacting protein (STYX) is a catalytically inactive member of the dual-specificity phosphatases (DUSPs) family. Whereas the role of DUSPs in cellular signaling is well explored, the function of STYX is still unknown. Here, we identify STYX as a spatial regulator of ERK s...

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Hlavní autoři: Reiterer, Veronika, Fey, Dirk, Kolch, Walter, Kholodenko, Boris N., Farhan, Hesso
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732994/
https://ncbi.nlm.nih.gov/pubmed/23847209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301985110
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