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Drug Efficacy Testing in Mice
The traditional path of drug development passes from in vitro screening and response assessment to validation of drug efficacy in cell line xenografts. While xenografts have their merits, historically, more often than not, they have not served as an accurate predictor of drug efficacy in humans. The...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732649/ https://ncbi.nlm.nih.gov/pubmed/21823029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2011_160 |
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