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Drug Efficacy Testing in Mice

The traditional path of drug development passes from in vitro screening and response assessment to validation of drug efficacy in cell line xenografts. While xenografts have their merits, historically, more often than not, they have not served as an accurate predictor of drug efficacy in humans. The...

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Detalhes bibliográficos
Main Authors: Kim, William Y., Sharpless, Norman E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732649/
https://ncbi.nlm.nih.gov/pubmed/21823029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/82_2011_160
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