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Opportunities and Challenges for use of Tumor Spheroids as Models to Test Drug Delivery and Efficacy
Multicellular spheroids are three dimensional in vitro microscale tissue analogs. The current article examines the suitability of spheroids as an in vitro platform for testing drug delivery systems. Spheroids model critical physiologic parameters present in vivo, including complex multicellular arch...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436947/ https://ncbi.nlm.nih.gov/pubmed/22613880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.04.045 |
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