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Optimization of Aqueous Biphasic Tumor Spheroid Microtechnology for Anti-Cancer Drug Testing in 3D Culture

Tumor spheroids are three-dimensional clusters of cancer cells that exhibit characteristics of poorly perfused tumors and hence present a relevant model for testing the efficacy of anti-cancer compounds. The use of spheroids for drug screening is hindered by technological complexities for high throu...

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Detalhes bibliográficos
Main Authors: Lemmo, Stephanie, Atefi, Ehsan, Luker, Gary D., Tavana, Hossein
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159185/
https://ncbi.nlm.nih.gov/pubmed/25221631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-014-0349-4
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