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Engineered Breast Cancer Cell Spheroids Reproduce Biologic Properties of Solid Tumors

Solid tumors develop as three-dimensional tissue constructs. As tumors grow larger, spatial gradients of nutrients and oxygen and inadequate diffusive supply to cells distant from vasculature develops. Hypoxia initiates signaling and transcriptional alterations to promote survival of cancer cells an...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Adv Healthc Mater
Päätekijät: Ham, Stephanie L., Joshi, Ramila, Luker, Gary D., Tavana, Hossein
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142748/
https://ncbi.nlm.nih.gov/pubmed/27603912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600644
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