Somatic profiling of the epidermal growth factor receptor pathway in tumours from patients with advanced colorectal cancer, treated with chemotherapy ± cetuximab

PURPOSE: To study the somatic molecular profile of the epidermal growth factor receptor (EGFR) pathway in advanced CRC (aCRC), its relationship to prognosis, the site of the primary and metastases, and response to cetuximab. EXPERIMENTAL DESIGN: We used Sequenom and Pyrosequencing for high-throughpu...

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Détails bibliographiques
Auteurs principaux: Smith, Christopher G., Fisher, David, Claes, Bart, Maughan, Timothy S., Idziaszczyk, Shelley, Peuteman, Gilian, Harris, Rebecca, James, Michelle D., Meade, Angela, Jasani, Bharat, Adams, Richard A., Kenny, Sarah, Kaplan, Richard, Lambrechts, Diether, Cheadle, Jeremy P.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732482/
https://ncbi.nlm.nih.gov/pubmed/23741067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2581
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