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Accumulation of pDC: roles in disease pathogenesis and targets for immunotherapy
Plasmacytoid dendritic cells (pDC) secrete type I interferons (IFN-I) in response to viruses and RNA/DNA/immunocomplexes. IFN-I confer resistance to viral infections and promote innate and adaptive immune responses. PDC also produce cytokines and chemokines that influence recruitment and function of...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3732170/ https://ncbi.nlm.nih.gov/pubmed/20853492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040602 |
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