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SLAMF9 regulates pDC homeostasis and function in health and disease

SLAMF9 belongs to the conserved lymphocytic activation molecule family (SLAMF). Unlike other SLAMs, which have been extensively studied, the role of SLAMF9 in the immune system remained mostly unexplored. By generating CRISPR/Cas9 SLAMF9 knockout mice, we analyzed the role of this receptor in plasma...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Sever, Lital, Radomir, Lihi, Strim, Kristin, Weiner, Anna, Shchottlender, Nofar, Lewinsky, Hadas, Barak, Avital F., Friedlander, Gilgi, Ben-Dor, Shifra, Becker-Herman, Shirly, Shachar, Idit
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6697803/
https://ncbi.nlm.nih.gov/pubmed/31346085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1900079116
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