CD84 regulates PD-1/PD-L1 expression and function in chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is characterized by clonal proliferation and progressive accumulation of mature B lymphocytes in the peripheral blood, lymphoid tissues, and bone marrow. CLL is characterized by profound immune defects leading to severe infectious complications. T cells are numeric...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Lewinsky, Hadas, Barak, Avital F., Huber, Victoria, Kramer, Matthias P., Radomir, Lihi, Sever, Lital, Orr, Irit, Mirkin, Vita, Dezorella, Nili, Shapiro, Mika, Cohen, Yosef, Shvidel, Lev, Seiffert, Martina, Herishanu, Yair, Becker-Herman, Shirly, Shachar, Idit
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264738/
https://ncbi.nlm.nih.gov/pubmed/30277471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI96610
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