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Microbiota induces tonic CCL2 systemic levels that control pDC trafficking in steady state
Plasmacytoid dendritic cells (pDCs) detect viruses initiating antiviral IFN-I responses. The microbiota is known to shape immune responses, but whether it influences pDC homeostasis and/or function is poorly understood. By comparing pDCs in germ-free and specific pathogen-free mice, we found that th...
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| Gepubliceerd in: | Mucosal Immunol |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2016
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5423869/ https://ncbi.nlm.nih.gov/pubmed/27827374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.99 |
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