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Incorporating parental information into family-based association tests

Assumptions regarding the true underlying genetic model, or mode of inheritance, are necessary when quantifying genetic associations with disease phenotypes. Here we propose new methods to ascertain the underlying genetic model from parental data in family-based association studies. Specifically, fo...

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Detalhes bibliográficos
Main Authors: Yu, Zhaoxia, Gillen, Daniel, Li, Carey F., Demetriou, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732025/
https://ncbi.nlm.nih.gov/pubmed/23266418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs048
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