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Accounting for Linkage in Family-Based Tests of Association with Missing Parental Genotypes

In studies of complex diseases, a common paradigm is to conduct association analysis at markers in regions identified by linkage analysis, to attempt to narrow the region of interest. Family-based tests for association based on parental transmissions to affected offspring are often used in fine-mapp...

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Autori principali: Martin, Eden R., Bass, Meredyth P., Hauser, Elizabeth R., Kaplan, Norman L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society of Human Genetics 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1180482/
https://ncbi.nlm.nih.gov/pubmed/14551902
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