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Incorporating parental information into family-based association tests

Assumptions regarding the true underlying genetic model, or mode of inheritance, are necessary when quantifying genetic associations with disease phenotypes. Here we propose new methods to ascertain the underlying genetic model from parental data in family-based association studies. Specifically, fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Zhaoxia, Gillen, Daniel, Li, Carey F., Demetriou, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3732025/
https://ncbi.nlm.nih.gov/pubmed/23266418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biostatistics/kxs048
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