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Clinical pharmacological properties of mipomersen (Kynamro), a second generation antisense inhibitor of apolipoprotein B

Mipomersen is a second generation antisense oligonucleotide that targets apolipoprotein B. It has been studied thoroughly in clinical trials (more than 800 subjects), including four randomized double-blind placebo controlled phase 3 studies involving 391 patients, and is in registration for the trea...

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Detalles Bibliográficos
Main Authors: Crooke, Stanley T, Geary, Richard S
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731601/
https://ncbi.nlm.nih.gov/pubmed/23013161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04469.x
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