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Drug-conjugated antibodies for the treatment of cancer
Despite considerable effort, application of monoclonal antibody technology has had only modest success in improving treatment outcomes in patients with solid tumours. Enhancing the cancer cell-killing activity of antibodies through conjugation to highly potent cytotoxic ‘payloads’ to create antibody...
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Science Inc
2013
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731599/ https://ncbi.nlm.nih.gov/pubmed/23173552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12044 |
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