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Drug-conjugated antibodies for the treatment of cancer
Despite considerable effort, application of monoclonal antibody technology has had only modest success in improving treatment outcomes in patients with solid tumours. Enhancing the cancer cell-killing activity of antibodies through conjugation to highly potent cytotoxic ‘payloads’ to create antibody...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731599/ https://ncbi.nlm.nih.gov/pubmed/23173552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12044 |
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