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Drug-conjugated antibodies for the treatment of cancer

Despite considerable effort, application of monoclonal antibody technology has had only modest success in improving treatment outcomes in patients with solid tumours. Enhancing the cancer cell-killing activity of antibodies through conjugation to highly potent cytotoxic ‘payloads’ to create antibody...

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Библиографические подробности
Главный автор: Lambert, John M
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731599/
https://ncbi.nlm.nih.gov/pubmed/23173552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12044
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