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Drug-conjugated antibodies for the treatment of cancer
Despite considerable effort, application of monoclonal antibody technology has had only modest success in improving treatment outcomes in patients with solid tumours. Enhancing the cancer cell-killing activity of antibodies through conjugation to highly potent cytotoxic ‘payloads’ to create antibody...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731599/ https://ncbi.nlm.nih.gov/pubmed/23173552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12044 |
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