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Antibody–Drug Conjugates (ADCs) for Personalized Treatment of Solid Tumors: A Review

Attaching a cytotoxic “payload” to an antibody to form an antibody–drug conjugate (ADC) provides a mechanism for selective delivery of the cytotoxic agent to cancer cells via the specific binding of the antibody to cancer-selective cell surface molecules. The first ADC to receive marketing authoriza...

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Detalhes bibliográficos
Publicado no:Adv Ther
Main Authors: Lambert, John M., Morris, Charles Q.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Healthcare 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427099/
https://ncbi.nlm.nih.gov/pubmed/28361465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12325-017-0519-6
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