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Viral degradasome hijacks mitochondria to suppress innate immunity

The balance between the innate immunity of the host and the ability of a pathogen to evade it strongly influences pathogenesis and virulence. The two nonstructural (NS) proteins, NS1 and NS2, of respiratory syncytial virus (RSV) are critically required for RSV virulence. Together, they strongly supp...

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Détails bibliographiques
Auteurs principaux: Goswami, Ramansu, Majumdar, Tanmay, Dhar, Jayeeta, Chattopadhyay, Saurabh, Bandyopadhyay, Sudip K, Verbovetskaya, Valentina, Sen, Ganes C, Barik, Sailen
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731571/
https://ncbi.nlm.nih.gov/pubmed/23877405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.98
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