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Extraribosomal L13a Is a Specific Innate Immune Factor for Antiviral Defense

We report a novel extraribosomal innate immune function of mammalian ribosomal protein L13a, whereby it acts as an antiviral agent. We found that L13a is released from the 60S ribosomal subunit in response to infection by respiratory syncytial virus (RSV), an RNA virus of the Pneumovirus genus and a...

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Detalhes bibliográficos
Main Authors: Mazumder, Barsanjit, Poddar, Darshana, Basu, Abhijit, Kour, Ravinder, Verbovetskaya, Valentina, Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136244/
https://ncbi.nlm.nih.gov/pubmed/24899178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01129-14
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