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Unique nonstructural proteins of Pneumonia Virus of Mice (PVM) promote degradation of interferon (IFN) pathway components and IFN-stimulated gene proteins

Pneumonia Virus of Mice (PVM) is the only virus that shares the Pneumovirus genus of the Paramyxoviridae family with Respiratory Syncytial Virus (RSV). A deadly mouse pathogen, PVM has the potential to serve as a robust animal model of RSV infection, since human RSV does not fully replicate the huma...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Dhar, Jayeeta, Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131486/
https://ncbi.nlm.nih.gov/pubmed/27905537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38139
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