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Absence of Endochondral Ossification and Craniosynostosis in Posterior Frontal Cranial Sutures of Axin2(−/−) Mice

During the first month of life, the murine posterior-frontal suture (PF) of the cranial vault closes through endochondral ossification, while other sutures remain patent. These processes are tightly regulated by canonical Wnt signaling. Low levels of active canonical Wnt signaling enable endochondra...

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Detalhes bibliográficos
Main Authors: Behr, Björn, Longaker, Michael T., Quarto, Natalina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731366/
https://ncbi.nlm.nih.gov/pubmed/23936395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070240
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