Craniosynostosis of Coronal Suture in Twist1(+/−) Mice Occurs Through Endochondral Ossification Recapitulating the Physiological Closure of Posterior Frontal Suture

Craniosynostosis, the premature closure of cranial suture, is a pathologic condition that affects 1/2000 live births. Saethre-Chotzen syndrome is a genetic condition characterized by craniosynostosis. The Saethre-Chotzen syndrome, which is defined by loss-of-function mutations in the TWIST gene, is...

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Main Authors: Behr, Björn, Longaker, Michael T., Quarto, Natalina
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Research Foundation 2011
Assuntos:
Physiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3143731/
https://ncbi.nlm.nih.gov/pubmed/21811467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00037
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