Medical treatment of craniosynostosis: Recombinant Noggin inhibits coronal suture closure in the rat craniosynostosis model

INTRODUCTION: The mechanisms underlying craniosynostosis remains unknown. However, mutations in FGFR2 are associated with craniosynostotic syndromes. We previously compared gene expression patterns of patent and synostosing coronal sutures in the nude rat and demonstrated down regulation of Noggin i...

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Hlavní autoři: Shen, K, Krakora, SM, Cunningham, M, Singh, M, Wang, X, Hu, FZ, Post, JC, Ehrlich, GD
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2762788/
https://ncbi.nlm.nih.gov/pubmed/19627528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-6343.2009.01460.x
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