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Absence of Endochondral Ossification and Craniosynostosis in Posterior Frontal Cranial Sutures of Axin2(−/−) Mice

During the first month of life, the murine posterior-frontal suture (PF) of the cranial vault closes through endochondral ossification, while other sutures remain patent. These processes are tightly regulated by canonical Wnt signaling. Low levels of active canonical Wnt signaling enable endochondra...

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Autori principali: Behr, Björn, Longaker, Michael T., Quarto, Natalina
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731366/
https://ncbi.nlm.nih.gov/pubmed/23936395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070240
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