Distinct Binding and Immunogenic Properties of the Gonococcal Homologue of Meningococcal Factor H Binding Protein

Neisseria meningitidis is a leading cause of sepsis and meningitis. The bacterium recruits factor H (fH), a negative regulator of the complement system, to its surface via fH binding protein (fHbp), providing a mechanism to avoid complement-mediated killing. fHbp is an important antigen that elicits...

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Bibliografiska uppgifter
Huvudupphovsmän: Jongerius, Ilse, Lavender, Hayley, Tan, Lionel, Ruivo, Nicola, Exley, Rachel M., Caesar, Joseph J. E., Lea, Susan M., Johnson, Steven, Tang, Christoph M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2013
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731240/
https://ncbi.nlm.nih.gov/pubmed/23935503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003528
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