GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

Glucose-regulated protein 78 (GRP78) is an endoplasmic reticulum (ER)-resident chaperone and a major regulator of the unfolded protein response (UPR). Accumulating evidence indicate that GRP78 is overexpressed in many cancer cell lines, and contributes to the invasion and metastasis in many human tu...

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Autori principali: Firczuk, M, Gabrysiak, M, Barankiewicz, J, Domagala, A, Nowis, D, Kujawa, M, Jankowska-Steifer, E, Wachowska, M, Glodkowska-Mrowka, E, Korsak, B, Winiarska, M, Golab, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730435/
https://ncbi.nlm.nih.gov/pubmed/23887632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.265
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