GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy

Glucose-regulated protein 78 (GRP78) is an endoplasmic reticulum (ER)-resident chaperone and a major regulator of the unfolded protein response (UPR). Accumulating evidence indicate that GRP78 is overexpressed in many cancer cell lines, and contributes to the invasion and metastasis in many human tu...

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Main Authors: Firczuk, M, Gabrysiak, M, Barankiewicz, J, Domagala, A, Nowis, D, Kujawa, M, Jankowska-Steifer, E, Wachowska, M, Glodkowska-Mrowka, E, Korsak, B, Winiarska, M, Golab, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730435/
https://ncbi.nlm.nih.gov/pubmed/23887632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.265
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