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Aminolevulinic Acid (ALA) as a Prodrug in Photodynamic Therapy of Cancer
Aminolevulinic acid (ALA) is an endogenous metabolite normally formed in the mitochondria from succinyl-CoA and glycine. Conjugation of eight ALA molecules yields protoporphyrin IX (PpIX) and finally leads to formation of heme. Conversion of PpIX to its downstream substrates requires the activity of...
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| Published in: | Molecules |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6263343/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16054140 |
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