Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing

Despite remarkable efforts, metastatic melanoma (MM) still presents with significant mortality. Recently, mono-chemotherapies are increasingly replenished by more cancer-specific combination therapies involving death ligands and drugs interfering with cell signaling. Still, MM remains a fatal diseas...

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Detalhes bibliográficos
Main Authors: Vörsmann, H, Groeber, F, Walles, H, Busch, S, Beissert, S, Walczak, H, Kulms, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730422/
https://ncbi.nlm.nih.gov/pubmed/23846221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.249
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