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Voxelized Computational Model for Convection-Enhanced Delivery in the Rat Ventral Hippocampus: Comparison with In Vivo MR Experimental Studies

Convection-enhanced delivery (CED) is a promising local delivery technique for overcoming the blood–brain barrier (BBB) and treating diseases of the central nervous system (CNS). For CED, therapeutics are infused directly into brain tissue and the drug agent is spread through the extracellular space...

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Detalhes bibliográficos
Main Authors: Kim, Jung Hwan, Astary, Garrett W., Kantorovich, Svetlana, Mareci, Thomas H., Carney, Paul R., Sarntinoranont, Malisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3730263/
https://ncbi.nlm.nih.gov/pubmed/22532321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-012-0566-8
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