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Influence of neuropathology on convection-enhanced delivery in the rat hippocampus.

Local drug delivery techniques, such as convention-enhanced delivery (CED), are promising novel strategies for delivering therapeutic agents otherwise limited by systemic toxicity and blood-brain-barrier restrictions. CED uses positive pressure to deliver infusate homogeneously into interstitial spa...

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Detalhes bibliográficos
Main Authors: Svetlana Kantorovich, Garrett W Astary, Michael A King, Thomas H Mareci, Malisa Sarntinoranont, Paul R Carney
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3832660?pdf=render
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