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Conformational Stability of Fibrillar Amyloid-Beta Oligomers via Protofilament Pair Formation – A Systematic Computational Study
Amyloid-[Image: see text] (A[Image: see text]) oligomers play a crucial role in Alzheimer’s disease due to their neurotoxic aggregation properties. Fibrillar A[Image: see text] oligomerization can lead to protofilaments and protofilament pairs via oligomer elongation and oligomer association, respec...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Public Library of Science
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729696/ https://ncbi.nlm.nih.gov/pubmed/23936224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070521 |
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