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Conformational Stability of Fibrillar Amyloid-Beta Oligomers via Protofilament Pair Formation – A Systematic Computational Study
Amyloid-[Image: see text] (A[Image: see text]) oligomers play a crucial role in Alzheimer’s disease due to their neurotoxic aggregation properties. Fibrillar A[Image: see text] oligomerization can lead to protofilaments and protofilament pairs via oligomer elongation and oligomer association, respec...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729696/ https://ncbi.nlm.nih.gov/pubmed/23936224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070521 |
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