The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors

The sensitivity of only a few tumors to anti-epidermal growth factor receptor EGFR tyrosine kinase inhibitors (TKIs) can be explained by the presence of EGFR tyrosine kinase (TK) domain mutations. In addition, such mutations were rarely found in tumor types other than lung, such as pancreatic and he...

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Bibliografiske detaljer
Main Authors: Chang, Xiaofei, Izumchenko, Eugene, Solis, Luisa M., Kim, Myoung Sook, Chatterjee, Aditi, Ling, Shizhang, Monitto, Constance L., Harari, Paul M., Hidalgo, Manuel, Goodman, Steve N., Wistuba, Ignacio I., Bedi, Atul, Sidransky, David
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729565/
https://ncbi.nlm.nih.gov/pubmed/23935914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068966
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