The Relative Expression of Mig6 and EGFR Is Associated with Resistance to EGFR Kinase Inhibitors

The sensitivity of only a few tumors to anti-epidermal growth factor receptor EGFR tyrosine kinase inhibitors (TKIs) can be explained by the presence of EGFR tyrosine kinase (TK) domain mutations. In addition, such mutations were rarely found in tumor types other than lung, such as pancreatic and he...

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Autori principali: Chang, Xiaofei, Izumchenko, Eugene, Solis, Luisa M., Kim, Myoung Sook, Chatterjee, Aditi, Ling, Shizhang, Monitto, Constance L., Harari, Paul M., Hidalgo, Manuel, Goodman, Steve N., Wistuba, Ignacio I., Bedi, Atul, Sidransky, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729565/
https://ncbi.nlm.nih.gov/pubmed/23935914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068966
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