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Role of Nucleic Acid–Sensing TLRs in Diverse Autoantibody Specificities and Anti-nuclear Antibody–Producing B Cells

Nucleic acid (NA)–sensing TLRs (NA-TLRs) promote the induction of anti-nuclear Abs in systemic lupus erythematosus. However, the extent to which other nonnuclear pathogenic autoantibody specificities that occur in lupus and independently in other autoimmune diseases depend on NA-TLRs, and which immu...

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Autores principales: Koh, Yi Ting, Scatizzi, John C., Gahan, Jennifer D., Lawson, Brian R., Baccala, Roberto, Pollard, K. Michael, Beutler, Bruce A., Theofilopoulos, Argyrios N., Kono, Dwight H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729324/
https://ncbi.nlm.nih.gov/pubmed/23589617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202986
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