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Influences of Crowded Cellular Environments on Protein Folding, Binding, and Oligomerization: Biological Consequences and Potentials of Atomistic Modeling
Recent experiments inside cells and in cytomimetic conditions have demonstrated that the crowded environments found therein can significantly reshape the energy landscapes of individual protein molecules and their oligomers. The resulting shifts in populations of conformational and oligomeric states...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3729036/ https://ncbi.nlm.nih.gov/pubmed/23395796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.01.064 |
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