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Positive regulation of meiotic DNA double-strand break formation by activation of the DNA damage checkpoint kinase Mec1(ATR)

During meiosis, formation and repair of programmed DNA double-strand breaks (DSBs) create genetic exchange between homologous chromosomes—a process that is critical for reductional meiotic chromosome segregation and the production of genetically diverse sexually reproducing populations. Meiotic DSB...

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Detalhes bibliográficos
Main Authors: Gray, Stephen, Allison, Rachal M., Garcia, Valerie, Goldman, Alastair S. H., Neale, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728922/
https://ncbi.nlm.nih.gov/pubmed/23902647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130019
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