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A Family-Based Probabilistic Method for Capturing De Novo Mutations from High-Throughput Short-Read Sequencing Data

Recent advances in high-throughput DNA sequencing technologies and associated statistical analyses have enabled in-depth analysis of whole-genome sequences. As this technology is applied to a growing number of individual human genomes, entire families are now being sequenced. Information contained w...

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Detalles Bibliográficos
Main Authors: Cartwright, Reed A., Hussin, Julie, Keebler, Jonathan E. M., Stone, Eric A., Awadalla, Philip
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728889/
https://ncbi.nlm.nih.gov/pubmed/22499693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1713
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