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GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells

Somatic mutations in GNAQ gene were described as being the main oncogenic activation in uveal melanomas, whereas mutations in BRAF gene have been described as a key genetic alteration that contributes to skin melanoma development. We have previously reported differential activation of the MAPK and A...

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Main Authors: Pópulo, Helena, Tavares, Sandra, Faustino, Alexandra, Nunes, Joana B., Lopes, José Manuel, Soares, Paula
Formáid: Artigo
Teanga:Inglês
Foilsithe: PeerJ Inc. 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728761/
https://ncbi.nlm.nih.gov/pubmed/23904987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.104
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