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SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma

BACKGROUND: SDHD promoter mutations were reported in 4–10% of cutaneous melanomas. The advanced clinico-pathological and patient survival association with SDHD mutation and/or expression in cutaneous melanoma remains controversial. OBJECTIVES: To evaluate the presence of SDHD promoter mutations and...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Pópulo, Helena, Batista, Rui, Sampaio, Cristina, Pardal, Joana, Lopes, José Manuel, Soares, Paula
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491217/
https://ncbi.nlm.nih.gov/pubmed/28662141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180392
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