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GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells
Somatic mutations in GNAQ gene were described as being the main oncogenic activation in uveal melanomas, whereas mutations in BRAF gene have been described as a key genetic alteration that contributes to skin melanoma development. We have previously reported differential activation of the MAPK and A...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
PeerJ Inc.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3728761/ https://ncbi.nlm.nih.gov/pubmed/23904987 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.104 |
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