Minor introns are embedded molecular switches regulated by highly unstable U6atac snRNA

Eukaryotes have two types of spliceosomes, comprised of either major (U1, U2, U4, U5, U6) or minor (U11, U12, U4atac, U6atac; <1%) snRNPs. The high conservation of minor introns, typically one amidst many major introns in several hundred genes, despite their poor splicing, has been a long-standin...

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Detalhes bibliográficos
Main Authors: Younis, Ihab, Dittmar, Kimberly, Wang, Wei, Foley, Shawn W, Berg, Michael G, Hu, Karen Y, Wei, Zhi, Wan, Lili, Dreyfuss, Gideon
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2013
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728624/
https://ncbi.nlm.nih.gov/pubmed/23908766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00780
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