Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy

Previous studies showed that knockdown of ITSN-1s (KD(ITSN)), an endocytic protein involved in regulating lung vascular permeability and endothelial cells (ECs) survival, induced apoptotic cell death, a major obstacle in developing a cell culture system with prolonged ITSN-1s inhibition(1). Using ca...

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Detaylı Bibliyografya
Asıl Yazarlar: Bardita, Cristina, Predescu, Dan, Predescu, Sanda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MyJove Corporation 2013
Konular:
Bioengineering
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728359/
https://ncbi.nlm.nih.gov/pubmed/23851900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50316
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