Fractalkine Depresses Cardiomyocyte Contractility

BACKGROUND: Our laboratory reported that male mice with cardiomyocyte-selective knockout of the prostaglandin E(2) EP4 receptor sub-type (EP4 KO) exhibit reduced cardiac function. Gene array on left ventricles (LV) showed increased fractalkine, a chemokine implicated in heart failure. We therefore h...

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Bibliografske podrobnosti
Main Authors: Taube, David, Xu, Jiang, Yang, Xiao-Ping, Undrovinas, Albertas, Peterson, Edward, Harding, Pamela
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728327/
https://ncbi.nlm.nih.gov/pubmed/23936109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069832
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