Compound A, a Selective Glucocorticoid Receptor Modulator, Enhances Heat Shock Protein Hsp70 Gene Promoter Activation

Compound A possesses glucocorticoid receptor (GR)-dependent anti-inflammatory properties. Just like classical GR ligands, Compound A can repress NF-κB-mediated gene expression. However, the monomeric Compound A-activated GR is unable to trigger glucocorticoid response element-regulated gene expressi...

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Detalhes bibliográficos
Main Authors: Beck, Ilse M., Drebert, Zuzanna J., Hoya-Arias, Ruben, Bahar, Ali A., Devos, Michael, Clarisse, Dorien, Desmet, Sofie, Bougarne, Nadia, Ruttens, Bart, Gossye, Valerie, Denecker, Geertrui, Lievens, Sam, Bracke, Marc, Tavernier, Jan, Declercq, Wim, Gevaert, Kris, Berghe, Wim Vanden, Haegeman, Guy, De Bosscher, Karolien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728325/
https://ncbi.nlm.nih.gov/pubmed/23935933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069115
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